A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/16 (2006.01) A61K 9/70 (2006.01) A61K 35/74 (2006.01) A61K 47/30 (2006.01) A61K 47/42 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2757449
The present invention provides a methods and compositions for treating a patient having a skin condition characterized by vascular hyper-reactivity, such as chronic or episodic flushing or blushing, and/or rosacea. The method comprises applying a topical composition to affected areas of the patient's skin. The topical composition comprises an effective amount of a botulinum neurotoxin for decreasing vasodilation in cutaneous microvasculature, and a carrier for effectively transporting the botulinum toxin to the cutaneous microvasculature. The invention thereby provides a safe, effective, comfortable, and/or convenient manner of treating vascular hyper-reactivity in skin.
La présente invention porte sur des procédés et des compositions de traitement d'un patient ayant une affection caractérisée par une hyperréactivité vasculaire, telle qu'une bouffée congestive ou un rougissement chroniques ou épisodiques et/ou de l'acné. Le procédé comprend l'application d'une composition topique aux zones affectées de la peau du patient. La composition topique comprend une quantité efficace d'une neurotoxine botulique destinée à diminuer la vasodilatation dans la microvasculature cutanée et un support destiné à transporter efficacement la toxine botulinique vers la microvasculature cutanée. L'invention apporte ainsi une façon sûre, efficace, confortable et/ou commode de traitement d'une hyperréactivité vasculaire de la peau.
Browne Dan
Du Alice
Ho Connie L.
Deeth Williams Wall Llp
Revance Therapeutics Inc.
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