Methods and compositions for treatment of cancer pain

Details Methods and compositions for treatment of cancer pain Methods and compositions for treatment of cancer pain

A - Human Necessities

61

K

A61K 31/196 (2006.01) C07C 229/42 (2006.01)

Patent

CA 2484546

The invention provides a method of treating cancer pain, e.g. bone cancer pain, in a subject in need of such treatment which comprises administering to the subject an effective amount of a COX-2 inhibitor; advantageously a compound of formula (I); wherein R, R1 R2, R3, R4, and R5 are as defined; a pharmaceutically acceptable salts thereof; or a pharmaceutically acceptable prodrug ester thereof.

L'invention concerne une méthode de traitement de la douleur cancéreuse, p. ex. de la douleur du cancer des os, chez un sujet nécessitant un traitement de ce type. Ladite méthode consiste à administrer à ce sujet une quantité efficace d'un inhibiteur de COX-2, pour plus d'efficacité d'un composé de formule (I), dans laquelle R, R¿1?, R¿2?, R¿3?, R¿4? et R¿5? sont tels que définis, de sels pharmaceutiquement acceptables dudit composé ou d'un promédicament ester pharmaceutiquement acceptable de ce dernier.

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