Methods and compositions for treatment of cancer using...

Details Methods and compositions for treatment of cancer using... Methods and compositions for treatment of cancer using...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 35/28 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2046916

The present invention provides methods useful in autologous bone marrow transplantation and cancer therapy. According to one aspect of the invention, bone marrow cells from a patient having cancer are treated with selected antisense oligonucleotides in order to deplete the bone marrow of malignant cells prior to infusion back into the bone marrow donor. In a separate embodiment, selected antisense oligonucleotides are administered systemically for anticancer therapy.

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