A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/48 (2006.01) A61K 9/28 (2006.01)
Patent
CA 2557999
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium~binding polymers and pharmaceutical compositions thereof Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.
L'invention concerne des procédés et des compositions pour le traitement de déséquilibres ioniques. Plus spécifiquement, l'invention concerne des compositions comprenant des polymères de liaison au sodium et des compositions pharmaceutiques de celles-ci. L'invention concerne également des procédés d'utilisation de ces compositions polymériques et pharmaceutiques dans des buts thérapeutiques et/ou prophylactiques. Des exemples de ces procédés comprennent le traitement de l'hypertension, de l'insuffisance cardiaque chronique, d'une maladie rénale en phase finale, de la cirrhose du foie, d'une insuffisance rénale chronique, d'une surcharge fluidique, ou d'une surcharge de sodium.
Alpern Robert
Buysse Jerry M.
Chang Han Ting
Charmot Dominique
Cope Michael James
Ilypsa Inc.
Relypsa
Ridout & Maybee Llp
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