Methods and compositions for treatment of preeclampsia

A - Human Necessities – 61 – K

Patent

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A61K 31/56 (2006.01)

Patent

CA 2563704

Methods and compositions for treating and/or preventing a pregnancy related disease or disorder are provided. The methods involve administration of 2- methoxyestradiol, or an analog thereof, to a subject. Also provided are methods for diagnosing or predicting a pregnancy related disease or disorder. The methods involve detection of 2-methoxyestradiol, or a precursor or metabolite thereof.

L'invention concerne des méthodes et des compositions de traitement et/ou de prévention d'une maladie ou d'un trouble associés à la grossesse. Les méthodes de l'invention consistent à administrer du 2-méthoxyestradiol, ou un analogue de celui-ci, à un sujet. L'invention concerne également des méthodes de diagnostic ou de prévision d'une maladie ou d'un trouble associé à la grossesse. Les méthodes consistent à détecter le 2-méthoxyestradiol, ou un précurseur ou un métabolite de celui-ci.

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