A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 38/48 (2006.01) C12N 7/01 (2006.01) C12N 9/64 (2006.01) C12N 15/63 (2006.01) C12N 15/86 (2006.01) C12N 15/864 (2006.01)
Patent
CA 2283639
The invention includes a composition comprising a recombinant adeno-associated viral vector comprising at least two adeno-associated virus inverted terminal repeats, a promoter/regulatory sequence, isolated DNA encoding Factor IX and accompanying 5' and 3' untranslated regions and a transcription termination signal, and methods of use thereof.
L'invention concerne une composition comprenant un vecteur viral recombiné adéno-associé présentant au moins deux répétitions terminales inversées de virus adéno-associé, une séquence promoteur/régulatrice, de l'ADN isolé codant le facteur IX et accompagnant les régions 5' et 3' non traduites ainsi qu'un signal d'achèvement de transcription, et ses modes d'utilisation.
Herzog Roland W.
High Katherine A.
Mbm Intellectual Property Law Llp
The Children's Hospital Of Philadelphia
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