Methods and compositions for using alveolar macrophage...

Details Methods and compositions for using alveolar macrophage... Methods and compositions for using alveolar macrophage...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A01K 67/027 (2006.01) A61K 38/46 (2006.01) A61P 11/00 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12P 7/64 (2006.01) C12Q 1/34 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2559936

The present invention is directed to methods and compositions for improving pulmonary surfactant catabolism. More specifically, the specification describes methods and compositions for making and using a lysosomal phospholipase A2 in methods for the diagnosis, and treatment of disorders of phospholipid catabolism such as pulmonary alveolar proteinosis.

La présente invention a trait à des procédés et des compositions permettant l'amélioration du catabolisme des tensioactifs pulmonaires. De manière plus spécifique, la présente invention a trait à des procédés et des compositions permettant la fabrication et l'utilisation d'une phospholipase A2 liposomale dans des procédés pour le diagnostic et le traitement de troubles de catabolisme des phospholipides tels que la protéinose alvéolaire pulmonaire.

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