C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) C40B 40/06 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2587189
The present invention concerns methods and compositions introducing miRNA activity or function into cells using synthetic nucleic acid molecules. Moreover, the present invention concerns methods and compositions for identifying miRNA with specific cellular functions that are relevant to therapeutic, diagnostic, and prognostic applications wherein synthetic miRNAs and/or miRNA inhibitors are used in library screening assays.
La présente invention concerne des procédés et des compositions utiles pour introduire l'activité ou la fonction mi-ARN dans des cellules au moyen de molécules d'acide nucléique de synthèse. Cette invention concerne également des procédés et des compositions permettant d'identifier un mi-ARN avec des fonctions cellulaires spécifiques qui relèvent d'applications thérapeutiques, de diagnostic et de pronostic dans lesquelles on utilise des mi-ARN de synthèse et/ou des inhibiteurs de mi-ARN dans des épreuves de criblage de bibliothèques.
Brown David
Byrom Mike
Cheng Angie
Devroe Eric
Ford Lance
Asuragen Inc.
Kirby Eades Gale Baker
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