Methods and compositions involving (s)-bucindolol

Details Methods and compositions involving (s)-bucindolol Methods and compositions involving (s)-bucindolol

C - Chemistry, Metallurgy

07

D

C07D 209/14 (2006.01) A61K 31/4045 (2006.01) A61P 9/06 (2006.01)

Patent

CA 2732513

Disclosed is bucindolol substantially free of its R-stereoisomer. Also disclosed are pharmaceutical compositions that include bucindolol substantially free of its R-stereoisomer or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. Also disclosed are methods of treating a patient that involve administering to the patient a therapeutically effective amount of a composition of the present invention. Formula (I).

L'invention porte sur du bucindolol pratiquement exempt de son stéréoisomère R. De plus, l'invention porte sur des compositions pharmaceutiques qui comprennent du bucindolol pratiquement exempt de son stéréoisomère R ou un sel pharmaceutiquement acceptable de celui-ci et un véhicule pharmaceutiquement acceptable. L'invention porte également sur des méthodes de traitement d'un patient qui comprennent l'administration au patient d'une quantité thérapeutiquement efficace d'une composition de la présente invention. Formule (I).

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