Methods and compositions of molecular profiling for disease...

Details Methods and compositions of molecular profiling for disease... Methods and compositions of molecular profiling for disease...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 15/12 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2743473

The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, in-cluding but not limited to gene expression product markers, alternative exon usage markers, and DNA polymorphisms associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determin-ing molecular profiles, and methods of analyzing results to provide a diagnosis.

La présente invention concerne des compositions, des kits et des procédés permettant le profilage moléculaire et le diagnostic du cancer, comprenant non exclusivement les marqueurs de produits d'expression génique, les marqueurs d'utilisationalternativedes exons et les polymorphismes de l'ADN associés au cancer. La présente invention porte en particulier sur des profils moléculaires associés au cancer de la thyroïde, sur des procédés de détermination de profils moléculaires et sur des procédés d'analyse des résultats pour poser un diagnostic.

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