A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 1/113 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2713872
Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.
Linvention concerne des compositions et des procédés utiles pour cibler et internaliser des molécules en cellules dintérêt et pour la pénétration de molécules dans des tissus dintérêt. Les compositions et les procédés sont basés sur des séquences de peptides qui sont internalisées sélectivement par une cellule, pénètrent un tissu, ou les deux. Linternalisation et la pénétration dun tissu selon linvention sont utiles pour délivrer des agents thérapeutiques et détectables aux cellules et aux tissus dintérêt.
Ruoslahti Erkki
Sugahara Kazuki
Teesalu Tambet
Burnham Institute For Medical Research
Gowling Lafleur Henderson Llp
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