Methods and compositions relating to alzheimer's disease

Details Methods and compositions relating to alzheimer's disease Methods and compositions relating to alzheimer's disease

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2578148

Methods and compositions relating to Alzheimer's disease are provided, including proteins that are differentially expressed in Alzheimer's disease as compared to the normal state. Further provided are methods, particularly experimental paradigms, for the identification of differential expressed proteins that are potential molecular targets for compounds to treat or prevent Alzheimer's disease. Also provided are methods for the identification and therapeutic use of compounds for the prevention and treatment of Alzheimer's disease.

La présente invention a pour objet des méthodes et des formulations en rapport avec la maladie d'Alzheimer. Elle inclut notamment des protéines qui sont exprimées différentiellement dans le cas de la maladie d~Alzheimer et chez une personne non atteinte. La présente invention décrit également des méthodes, et plus particulièrement des paradigmes expérimentaux, permettant l~identification de protéines exprimées différentiellement. Lesdites protéines constituent des cibles moléculaires potentielles pour des composés utilisés dans des traitements thérapeutiques ou prophylactiques de la maladie d'Alzheimer. La présente invention a également pour objet des méthodes permettant l~identification et l~emploi en tant que médicaments de composés utilisés dans des traitements thérapeutiques ou prophylactiques de la maladie d'Alzheimer.

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