A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/565 (2006.01) A61K 9/16 (2006.01) A61K 38/09 (2006.01) A61P 13/08 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2523830
The present invention relates to compositions comprising two sustained release formulations, the first being capable of releasing a gonadotropin releasing hormone composition and the second an estrogenic composition. The compositions of the invention can be employed for an improved androgen deprivation therapy of prostate cancer, in which therapy loss of bone mineral density and the occurrence and severity of hot flashes are minimized through the maintenance of a minimally adequate estrogen level.
La présente invention concerne des compositions renfermant deux formulations à libération prolongée, la première étant apte à libérer une composition de gonadolibérine, et la deuxième une composition oestrogénique. Lesdites compositions peuvent être utilisées en vue d'améliorer un traitement antiandrogène du cancer de la prostate, au cours duquel la déminéralisation osseuse due au traitement, ainsi que la survenue et l'intensité des bouffées de chaleur sont réduites au minimum grâce au maintien d'un taux d'oestrogènes minimal suffisant.
Curdy Catherine
Ducrey Bertrand
Heimgartner Frederic
Porchet Herve
Debiopharm S.a.
Robic
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