Methods and compositions using (-) norcisapride in...

A - Human Necessities – 61 – P

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A61P 1/00 (2006.01) A61K 31/426 (2006.01) A61K 31/445 (2006.01) A61K 31/4468 (2006.01) A61K 45/06 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2362488

The invention relates to methods and compositions for the prevention, treatment, or management of gastrointestinal disorders or symptoms thereof, employing two or more agents or compounds to provide a triple site action on 5- HT3 receptors, 5-HT4 receptors, and at least one of H2 receptors and proton pumps.

L'invention concerne des procédés et compositions destinés à la prévention, au traitement ou à la gestion de troubles gastro-intestinaux, ou de symptômes provoqués par ces troubles, et dans lesquels on utilise au moins deux agents ou composés, afin d'exercer une triple action de site sur les récepteurs de 5-HT¿3?, sur les récepteurs de 5-HT¿4?, et au moins sur un des récepteurs de H¿2? et sur les pompes à protons.

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