Methods and compositions using pde4 modulators for treatment...

A - Human Necessities – 61 – K

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Details

A61K 31/4035 (2006.01) A61K 31/506 (2006.01) A61K 31/515 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2585423

Methods of treating, preventing and/or managing a central nervous system injury/damage and related syndromes are disclosed. Specific methods encompass the administration of a PDE4 modulator alone or in combination with a second active agent. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.

L'invention porte sur des méthodes de traitement, de prévention et/ou de gestion d'une lésion/détérioration du système nerveux central et sur les syndromes afférents. Des méthodes spécifiques incluent l'administration d'un modulateur de PDE4 isolé ou en combinaison avec un deuxième agent actif. L'invention porte également sur des compositions pharmaceutiques, sur des formes posologiques à dose unitaire ainsi que sur des kits conçus pour être utilisés dans le cadre des procédés décrits dans l'invention.

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