C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) C12Q 1/26 (2006.01)
Patent
CA 2398940
The use of screening assays based on the role of human stearoyl-CoA desaturase- 1 ("hSCD1") in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, monounsaturated fatty acids., wax esters, and the like, is disclosed. Also disclosed are conventions useful in the prevention and/or treatment of such diseases.
L'invention concerne l'utilisation de méthodes de criblage basées sur le rôle de la stéaroyl-CoA désaturase-1 ("hSCD1") humaine dans les maladies, troubles ou pathologies humains liés aux niveaux sériques de triglycérides, de particules VLDL, HDL et LDL et de cholestérol total ou à la production de sécrétions par les muqueuses, aux acides gras monoinsaturés, aux esters de cire et analogues. L'invention concerne également des conventions utilisées dans la prévention et/ou le traitement desdites maladies.
Attie Alan D.
Brownlie Alison J.
Gray-Keller Mark P.
Hayden Michael R.
Miyazaki Makoto
Mbm Intellectual Property Law Llp
University Of British Columbia
Wisconsin Alumni Research Foundation
Xenon Genetics Inc.
Xenon Pharmaceuticals Inc.
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