A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 9/00 (2006.01) C12N 9/64 (2006.01) C12N 15/86 (2006.01) C12N 15/864 (2006.01)
Patent
CA 2410901
The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like).
L'invention utilise des parvovirus de recombinaison, et notamment un virus de recombinaison associé à adéno (rAAV) dans l'administration de gènes et de séquences d'ADN en thérapie génique, puis dans la manipulation du virus thérapeutique pour son conditionnement et son transport. L'invention permet d'administrer des vecteurs viraux thérapeutiques via rAAV fixé à des matrices de support (telles que sutures, matériaux implantables par voie chirurgicale, greffes et analogues).
Monahan Paul E.
Rabinowitz Joseph E.
Samulski Richard J.
Sim & Mcburney
University Of North Carolina At Chapel Hill
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