Methods and compounds for diagnosing coronary artery disease

C - Chemistry – Metallurgy – 07 – C

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C07C 323/25 (2006.01) A61K 49/00 (2006.01) C07C 217/02 (2006.01) C07C 217/08 (2006.01) C07C 247/04 (2006.01) C07C 255/24 (2006.01) C07C 317/28 (2006.01)

Patent

CA 2224109

The present invention relates generally to methods of diagnosis, evaluation and treatment of coronary artery disease in mammals using substituted catecholamines and compounds therefore. It also relates to the preparation, use and administration of these compounds which are useful in the diagnosis, evaluation and treatment of coronary artery disease by means of a feedback controlled drug delivery system that delivers exercise simulating agents which are capable of eliciting acute responses similar to those elicited by aerobic exercise.

La présente invention concerne d'une manière générale des procédés de diagnostic, d'évaluation et de traitement des affections des artères coronaires chez les mammifères au moyen de catécholamines substituées et de composés destinés à ces usages. L'invention concerne aussi la préparation, l'emploi et l'administration de ces composés, qui sont utiles dans le diagnostic, l'évaluation et le traitement d'affections des artères coronaires au moyen d'un système d'apport de médicaments commandé par rétroaction, qui fournit des agents de simulation de l'exercice physique capables de déclencher des réactions intenses, similaires à celles que produisent les exercices d'aérobic.

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