C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/06 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01) A61K 38/05 (2006.01) C07C 237/22 (2006.01) C07D 213/38 (2006.01) C07D 333/20 (2006.01) C07K 5/062 (2006.01) C07K 5/065 (2006.01) C07K 5/08 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2267634
Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
L'invention concerne des composés qui servent à inhiber la libération et/ou la synthèse du peptide beta -amyloïde et qui peuvent, de ce fait, être utilisés dans le traitement de la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques qui comprennent un composé inhibant la libération et/ou la synthèse du peptide beta -amyloïde, ainsi que des méthodes de traitement préventif ou thérapeutique de la maladie d'Alzheimer dans lesquelles on utilise lesdites compositions pharmaceutiques.
Audia James E.
Britton Thomas C.
Droste James J.
Eid Clark Norman
Folmer Beverly K.
Elan Pharmaceuticals Inc.
Eli Lilly & Company
Gowling Lafleur Henderson Llp
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