Methods and compounds for prevention and treatment of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/08 (2006.01) A61P 27/06 (2006.01) C07K 7/06 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2480388

A GPCR-like protein is described, as well as inhibitory/antagonistic compounds and compositions comprising such inhibitors/antagonists of the protein. Such compounds may be used for treating elevated intraocular pressure and conditions associated with elevated intraocular pressure, such as glaucoma.

L'invention concerne une protéine de type GPCR, ainsi que des composés inhibiteurs/antagonistes et des compositions comprenant de tels inhibiteurs/antagonistes. Ces composés peuvent servir dans le traitement de la pression intraoculaire élevée et des états qui y sont associés, par exemple le glaucome.

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