Methods and compounds for the diagnosis of inflammatory...

Details Methods and compounds for the diagnosis of inflammatory... Methods and compounds for the diagnosis of inflammatory...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12P 19/34 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2448265

Methods for the diagnosis of inflammatory bowel diseases and the identification of agents useful in the treatment of such diseases based upon the agent's effect on reducing Pim-2 expression. Figure 6 shows that Pim-2 is required for TNF-alpha-induced IL-6 expression in HeLa cells.

L'invention concerne des méthodes utilisées dans le diagnostic de maladies intestinales inflammatoires et dans l'identification d'agents utiles pour le traitement de ces maladies, en fonction de l'effet de l'agent sur la réduction de l'expression de Pim-2.

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