Methods and compounds for treating retinol-related diseases

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 235/40 (2006.01) A61K 31/192 (2006.01) A61K 31/195 (2006.01) A61K 31/216 (2006.01) A61K 31/235 (2006.01) A61P 27/02 (2006.01) C07C 57/42 (2006.01) C07C 61/40 (2006.01) C07C 62/34 (2006.01) C07C 235/24 (2006.01) C07C 237/04 (2006.01) C07C 237/16 (2006.01) C07C 237/24 (2006.01) C07C 323/23 (2006.01) C07C 323/50 (2006.01) C07D 307/10 (2006.01)

Patent

CA 2699773

Compounds that reduce serum retinol levels are used to treat ophthalmic conditions associated with the overproduction of waste products that accumulate during the course of the visual cycle. We describe methods, compounds, and compositions to treat, for example, the macular degenerations and dystrophies or to alleviate symptoms associated with such ophthalmic conditions.

Les composés qui réduisent les taux de rétinol dans le sérum sont utilisés pour traiter des états ophtalmiques associés à la surproduction de produits résiduaires qui s'accumulent pendant le cours du cycle visuel. Nous décrivons des procédés, des composés et des compositions pour traiter, par exemple, les dégénérescences maculaires et les dystrophies maculaires ou pour soulager des symptômes associés à de tels états ophtalmiques.

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