Methods and computer software products for transcriptional...

Details Methods and computer software products for transcriptional... Methods and computer software products for transcriptional...

G - Physics

01

N

G01N 33/48 (2006.01) C07H 21/04 (2006.01) C12Q 1/68 (2006.01) G01N 31/00 (2006.01)

Patent

CA 2378854

Methods and computer software products are provided for transcriptional annotation. In one embodiment of the invention, a region of the genome where the intensity of hybridization of all the probes are above a threshold value (usually the level of non-specific hybridization) is identified. The region may be identified by aligning the probes against the genome; walking through the genome to find regions where all consecutive probes have intensities above the threshold value.

Cette invention concerne des procédés et des produits logiciels pour annotation transcriptionnelle. Selon un mode de réalisation, on identifier une région du génome dans laquelle l'intensité d'hybridation de toutes les sondes se situe au-dessus d'une valeur de seuil (soit en général le niveau d'hybridation non spécifique). Le processus d'identification de la région consiste par exemple à mettre les sondes en regard du génome et à parcourir ce dernier pour localiser les régions dans lesquelles des sondes consécutives ont des intensités supérieures à la valeur de seuil.

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