Methods and computer systems for identifying target-specific...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2687292

The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to coded, labeled probes that are capable of binding to and identifying target molecules based on the probes' label codes. Methods, computers, and computer program products for identifying target-specific sequences for inclusion in the probes are also provided, as are methods of making and using such probes. The probes can be used in diagnostic, prognostic, quality control and screening applications.

La présente invention concerne des compositions et des procédés pour la détection et la quantification de molécules cibles individuelles dans des échantillons biomoléculaires. En particulier, l'invention concerne des sondes marquées et codées qui sont capables de se lier à des molécules cibles et de les identifier grâce aux codes de leurs marqueurs. L'invention concerne également des procédés, des ordinateurs et des progiciels d'identification de séquences spécifiques d'une cible pour les inclure dans les sondes, ainsi que des procédés de préparation et d'utilisation de ces sondes. Ces sondes peuvent être utilisées dans des applications de diagnostic, de pronostic, de contrôle de qualité et de criblage.

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