Methods and devices for sequencing nucleic acids

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2567822

The invention provides methods and devices for high throughput single molecule sequencing of a plurality of target nucleic acids using a universal primer. Devices of the invention comprise a plurality of oligonucleotides, each having the same sequence, bound to a solid support, and ligated to a plurality of target nucleic acids.

L'invention concerne des procédés et des dispositifs destinés au séquençage moléculaire à haut débit d'une pluralité d'acides nucléiques cibles, utilisant une amorce universelle. Les dispositifs de l'invention comprennent une pluralité d'oligonucléotides possédant chacun la même séquence, fixés à un support solide et ligaturés à une pluralité d'acides nucléiques cibles.

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