Methods and devices for transdermal electrotransport...

Details Methods and devices for transdermal electrotransport... Methods and devices for transdermal electrotransport...

A - Human Necessities

61

N

A61N 1/30 (2006.01)

Patent

CA 2656086

Electrotransport drug delivery devices, systems and methods for delivery of lofentanil or carfentanil are disclosed. The lofentanil or carfentanil may be provided as a water soluble salt (e.g., lofentanil or carfentanil hydrochloride), such as in a hydrogel formulation. A transdermal, electrotransport delivered dose of lofentanil or carfentanil is provided which is sufficient to induce analgesia in (e.g., adult) human patients suffering from chronic, acute and/or breakthrough pain.

La présente invention concerne des procédés, systèmes et dispositifs d'administration de médicaments par transport électrique pour l'administration de lofentanil ou de carfentanil. Le lofentanil ou le carfentanil peuvent être fournis sous forme de sel soluble dans l'eau (par exemple, le chlorhydrate de lofentanil ou de carfentanil), tel que dans une formulation d'hydrogel. L'invention concerne également une dose de lofentanil ou de carfentanil administrée par transport électrique transdermique, qui est suffisante pour induire une analgésie chez des patients humains (adultes, par exemple) souffrant d'une douleur chronique, aiguë et/ou instable.

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