Methods and dosage forms for increasing solubility of drug...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 9/48 (2006.01) A61K 31/18 (2006.01)

Patent

CA 2550866

Dosage forms and devices for enhancing controlled delivery of pharmaceutical agents by use of a drug core composition that increases the solubility of the pharmaceutical agent are described. The present invention provides a means of delivering high doses of poorly soluble drug in oral drug delivery systems that are convenient to swallow, for once-a-day administration.

La présente invention se rapporte à des formes posologiques et à des dispositifs permettant d'améliorer l'administration contrôlée d'agents pharmaceutiques, et qui font appel, pour ce faire, à une composition noyau augmentant la solubilité desdits agents pharmaceutiques. L'invention concerne un moyen permettant d'administrer des doses importantes d'un médicament peu soluble contenues dans des systèmes d'administration de médicament par voie orale qui sont faciles à avaler et destinés à une prise par jour.

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