A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/40 (2006.01) A61K 31/18 (2006.01) A61K 31/4035 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2508269
The present invention relates to methods and dosage forms for reducing and/or preventing the incidence of cardiovascular disease, including heart attacks, in individuals who are at risk, such as those individuals suffering from hypertension. The treatments and dosage forms of the present invention concern the administration of a diuretic, such as a thiazide diuretic like Thalitone®, either alone or in combination with an ACE-inhibitor, such as ramipril or ramiprilat like Altace®, to reduce and/or prevent the incidence of cardiovascular disease, namely, heart attacks or failure, in individuals who suffer from hypertension or are at risk.
L'invention concerne des procédés et des formes de dosage permettant de réduire et/ou de prévenir l'incidence de maladies cardiovasculaires, notamment des infarctus du myocarde, chez des individus à risque, tels que ceux souffrant d'hypertension. Les traitements et les formes de dosage de cette invention concernent l'administration d'un diurétique, notamment un diurétique thiazidique tel que le Thalitone®, seul ou en combinaison avec un inhibiteur de l'enzyme de conversion, notamment du ramipril ou du ramiprilat tel que de l'Altace®, en vue de réduire et/ou de prévenir l'incidence de maladies cardiovasculaires, tel que l'infarctus du myocarde ou la défaillance cardiaque, chez des individus souffrant d'hypertension ou étant à risque.
Califf Robert M.
Christian Victoria
Gregory Jefferson J.
Lipicky Raymond J.
Califf Robert M.
Christian Victoria
Gregory Jefferson J.
King Pharmaceuticals Inc.
Lipicky Raymond J.
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