Methods and formulations for improved bioavailability of...

Details Methods and formulations for improved bioavailability of... Methods and formulations for improved bioavailability of...

A - Human Necessities

61

K

A61K 31/57 (2006.01) A61K 9/14 (2006.01) A61P 15/00 (2006.01)

Patent

CA 2672888

Compositions comprising an antiprogestin and having improved bioavailability are provided. In one aspect, compositions comprising particles of an antiprogestin deposited on a carrier substrate are provided. In another aspect, compositions comprising a micronized antiprogestin are provided. Also provided is the use of compositions comprising an antiprogestin and having improved bioavailability for the treatment of endometriosis, uterine fibroids, dysmenorrhea, and meningiomas.

L'invention concerne des compositions comprenant une antiprogestine et ayant une biodisponibilité améliorée. Dans un aspect, l'invention concerne des compositions comprenant des particules d'une antiprogestine déposée sur un substrat vecteur. Dans un autre aspect, l'invention propose des compositions comprenant une antiprogestine micronisée. L'invention concerne également l'utilisation de compositions comprenant une antiprogestine et ayant une biodisponibilité améliorée pour le traitement de l'endométriose, des fibromyomes utérins, des dysménorrhées, et des méningiomes.

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