Methods and formulations for reducing circulating antibodies

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01) A61K 39/385 (2006.01) C07H 15/08 (2006.01) C07H 15/18 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2353620

The invention provides methods for reducing circulating levels of antibodies, particularly disease-associated antibodies. The methods entail administering effective amounts of epitope-presenting carriers to an individual. In other embodiments, ex vivo methods for reducing circulating levels of antibodies are provided which employ epitope-presenting carriers.

L'invention concerne des procédés permettant de réduire la concentration d'anticorps circulant, et notamment des anticorps associés à des maladies. Ces méthodes consistent à administrer à un individu des quantités efficaces de supports présentant des épitopes. Dans d'autres modes de réalisation, l'invention concerne des procédés utilisant des supports présentant des épitopes et permettant de réduire la concentration d'anticorps en circulation.

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