Methods and kits for analyzing genetic material of a fetus

Details Methods and kits for analyzing genetic material of a fetus Methods and kits for analyzing genetic material of a fetus

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2626757

A non-invasive method of analyzing a genetic material of a fetus is provided. The method is achieved by detecting a cell-free nucleus in a sample such as a transcervical specimen obtained from a pregnant woman and/or detecting in a cell-free nucleus at least one fetal-nucleus specific marker thereby identifying a fetal nucleus; and molecularly analyzing the genetic material in the fetal nucleus, thereby analyzing the genetic material of the fetus.

La présente invention a trait à un procédé non invasif d'analyse de matériau génétique d'un foetus. Le procédé s'exécute par la détection d'un nucleus exempt de cellules dans un échantillon tel qu'un spécimen transcervical obtenu à partir d'une femme enceinte et/ou la détection dans un nucleus exempt de cellules d'au moins un marqueur spécifique de nucleus foetal permettant ainsi l'identification d'un nucleus foetal; et l'analyse moléculaire du matériau génétique dans le nucleus foetal, permettant ainsi l'analyse du matériau génétique du foetus.

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