C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/19 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) A61P 35/02 (2006.01) A61P 37/04 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2599222
The present invention relates to methods and kits for detecting several polynucleotide sequence found to be indicative of a poor prognosis of B-CLL. All the polynucleotides are transcribed from a region on human chromosome 12p21-22. Most of the polynucleotides do not encode larger polypeptides, but may encode small peptides, they may function as RNAs. Four polynucleotides encode a novel protein, which in one preferred embodiment can be used as a cytokine, preferably as an interleukin. Furthermore the invention relates to methods and compositions for treating B-CLL in particular poor prognosis B-CLL.
Hertz Anne Mette Buhl
Kjems Jorgen
Leffers Henrik
Arhus Universitet
Clluone Therapeutics A/s
Gowling Lafleur Henderson Llp
H:s Rigshospitalet
LandOfFree
Methods and kits for diagnosing and treating b-cell chronic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and kits for diagnosing and treating b-cell chronic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and kits for diagnosing and treating b-cell chronic... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2059413