Methods and kits for diagnosis of multiple sclerosis in...

Details Methods and kits for diagnosis of multiple sclerosis in... Methods and kits for diagnosis of multiple sclerosis in...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2673595

Provided are methods and kits for determining the probability of a subject diagnosed with probable multiple sclerosis to develop definite diagnosis of multiple sclerosis by determining the expression level of polynucleotides which are differentially expressed between subjects diagnosed with probable multiple sclerosis and which further develop definite multiple sclerosis and unaffected subjects. Also provided are methods and kits for selecting a treatment regimen of a subject diagnosed with probable multiple sclerosis.

L'invention concerne des méthodes et des trousses permettant de déterminer le risque, pour un patient chez lequel une sclérose en plaques probable a été diagnostiquée, de développer une sclérose en plaques définie, par détermination du niveau d'expression de polynucléotides exprimés de manière différentielle entre des patients chez lesquels une sclérose en plaques probable a été diagnostiquée, et qui développeront ensuite une sclérose en plaques définie, et des patients sains. L'invention concerne également des méthodes et des trousses destinées à sélectionner un régime thérapeutique pour un patient chez lequel une sclérose en plaques probable a été diagnostiquée.

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