Methods and kits for investigating cancer

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2530057

The invention provides novel compositions, methods and uses, for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia and breast cancer. The invention further relates to genes that are differentially expressed in breast tissue of breast cancer patients versus those of normal "healthy" tissue. Differentially expressed genes for the identification of patients which are likely to respond to chemotherapy are also provided.

L'invention concerne de nouvelles compositions, ainsi que des méthodes et utilisations associées, pour la prédiction, le diagnostic, le pronostic, la prévention et le traitement des néoplasies malignes et du cancer du sein. L'invention concerne également des gènes qui sont exprimés de manière différentielle dans des tissus mammaires de patientes atteintes du cancer du sein par rapport à ceux de tissus "sains". L'invention concerne également des gènes exprimés de manière différentielle, servant à l'identification de patientes qui sont susceptibles de répondre à une chimiothérapie.

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