A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01)
Patent
CA 2518268
This invention provides methods and kits for maintaining pregnancy in mammals. Pregnancy is maintained by administration of effective amounts of luteinizing hormone (LH) or chorionic gonadotropin (CG). Both LH and CG may be used alone, in combination with each other, or in combination with growth hormone (GH) or follicle stimulating hormone (FSH). Hormones are administered on about Day 4 to about Day 7 following insemination. Effective amounts of LH range from about 10 micrograms to about 25 milligrams, preferably about 2 to about 8 mg, and of CG range from about 100 IU (international units) to about 2000 IU. Mammals treatable by the methods of this invention include ungulates and related mammals, including bovines. Kits provided by this invention include effective amounts of one or more hormones, a device for administering the hormone(s) and instructions. This invention also provides methods for treating follicular cysts and for synchronizing ovulation in mammals using LH.
L'invention porte sur des méthodes et des trousses permettant de fixer la gravidité chez des mammifères par administration d'une dose efficace d'hormone lutéïnisante (LH), de gonadotrophine chorionique (CG) qui peuvent s'utiliser seules ou ensemble ou combinées à de l'hormone de croissance (GH) ou à de l'hormone folliculostimulante (FSH), l'administration se faisant environ entre le jour 4 et le jour 7 suivant l'insémination. Les doses efficaces de LH vont d'environ 10 µg à environ 25 mg, et de préférence d'environ 2 à environ 8 mg, et celles de CG d'environ 100 UI (unités internationales) à environ 2000 UI. Les mammifères traitables par ces méthodes comprennent les ongulés et les mammifères apparentés dont les bovins. Lesdites trousses comportent des doses efficaces d'une ou plusieurs hormones, un dispositif d'administration et des instructions. L'invention porte également sur des méthodes de traitement de kystes folliculaires et de synchronisation de l'ovulation à l'aide de LH.
Colgin Mark
Hurst Roger
Mcsweeney Kevin
Newman Diane
Roth Jay W.
Aspenbio Inc.
Aspenbio Pharma Inc.
Mckay-Carey & Company
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