Methods and kits for predicting prognosis of multiple sclerosis

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2673469

Provided are methods and kits for predicting the prognosis of a subject diagnosed with multiple sclerosis by determining the expression level of polynucleotides which are differentially expressed between subjects diagnosed with multiple sclerosis and having good or poor clinical outcome. Also provided are methods and kits for selecting a treatment regimen of a subject diagnosed with multiple sclerosis.

L'invention concerne des méthodes et des trousses destinées à prédire le pronostic d'un patient chez lequel une sclérose en plaques a été diagnostiquée, par détermination du niveau d'expression de polynucléotides exprimés de manière différentielle entre des patients chez lesquels une sclérose en plaques a été diagnostiquée, et qui présentent une évolution clinique positive ou négative. L'invention concerne également des méthodes et des trousses destinées à sélectionner un régime thérapeutique pour un patient chez lequel une sclérose en plaques a été diagnostiquée.

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