Methods and kits for predicting risk for preterm labor

Details Methods and kits for predicting risk for preterm labor Methods and kits for predicting risk for preterm labor

G - Physics

01

N

G01N 33/68 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61B 10/00 (2006.01)

Patent

CA 2641049

The invention is directed to kits and methods that allow one to predict the risk for preterm labor in a pregnant woman. The inventors have discovered that various extracellular matrix components can be detected in cervical secretions. The quantification of certain extracellular matrix proteins found within cervical secretions can be used as a diagnostic for the biomechanical state of the cervix, which indicates whether preterm labor is likely. Some extracellular matrix components that can be found in cervical secretions include decorin, thrombospondins and matrix metalloproteinases.

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