A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/57 (2006.01) A61K 31/415 (2006.01) A61K 31/4174 (2006.01) C07K 16/40 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2284039
This invention provides methods of treating a subject suffering from a leiomyoma which comprise administering to the subject a therapeutically effective amount of an agent, or alternatively a plurality of agents, which inhibit specific metalloproteinases. This invention further provides diagnostic methods of determining whether a tumor in a subject is a leiomyoma. This invention further provides pharmaceutical compositions and kits for practicing the instant methods. Finally, this invention provides a method of determining whether an agent specifically inhibits certain metalloproteinases.
L'invention concerne des méthodes de traitement d'un sujet atteint d'un léiomyome, qui consistent à administrer au sujet une dose thérapeutiquement efficace d'un agent, ou d'une pluralité d'agents, inhibant des métalloprotéases spécifiques. L'invention concerne également des méthodes diagnostiques permettant de déterminer si une tumeur chez un sujet est un léiomyome. L'invention concerne, en outre, des compositions pharmaceutiques et des kits de mise en pratique des méthodes en question. Enfin, l'invention concerne une méthode permettant de déterminer si un agent inhibe spécifiquement certaines métalloprotéases.
Nowak Romona
Palmer Stephen S.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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