Methods and kits utilizing heparanase as a diagnostic marker...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/10 (2006.01) G01N 33/53 (2006.01) G01N 33/537 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2446962

Provided is a method of determining a presence, absence, or severity of a haemostatic disorder in a subject. The method is effected by determining a level of heparanase expression or activity in a biological sample obtained from the subject. Also provided are kits for use with the method.

La présente invention concerne une méthode de détermination d'une présence, absence, ou gravité d'un trouble hémostatique chez un sujet. Ladite méthode est mise en oeuvre par détermination d'un niveau d'expression d'héparanase ou d'activité dans un échantillon biologique prélevé chez le sujet. L'invention concerne également des matériels destinés à être utilisés avec ladite méthode.

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