C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) C40B 30/04 (2006.01) G01N 33/574 (2006.01) C07K 16/18 (2006.01) C40B 40/10 (2006.01)
Patent
CA 2691852
The present invention relates to rapid, sensitive methods for determining whether a subject has or is at risk of devel-oping lung cancer based on certain combinations of biomarkers, or biomarkers and biometric parameters. The methods consist of: a) quantifying in a test sample obtained from a subject, the amount of two or more biomarkers in a panel, the panel comprising at least one antibody and at least one antigen: b) comparing the amount of each biomarker quantified in the panel to a predetermined cutoff for said biomarker and assigning a score for each biomarker based on said comparison: c) combining the assigned score for each biomarker quantified in step b to obtain a total score for said subject: d) comparing the total score in step c with a predetermined total score and e) determining whether said subject has a risk of lung cancer based on the comparison in step d.
La présente invention porte sur des procédés sensibles et rapides pour déterminer si un sujet est sujet à un risque de développer un cancer du poumon ou développe un cancer du poumon sur la base de certaines combinaisons de biomarqueurs ou de certains biomarqueurs et paramètres biométriques.
Colpitts Tracey
Frost Stephen
Ramirez Javier
Russell Eric L.
Russell John C.
Abbott Laboratories
Torys Llp
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