Methods and materials for identifying agents which modulate...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2526845

The invention discloses compositions, compounds, apparatuses and methods of using them to study bone mineralization and identify agents that regulate bone mineralization. Methods of using bone mineralization gene profiles and signatures for compound screening and research are also disclosed. Reagents for modulating bone mineralization are provided for both therapeutic and research usage.

La présente invention concerne des compositions, des composés, des appareils et leurs procédés d'utilisation, qui permettent d'étudier la minéralisation osseuse et d'identifier des agents qui régulent la minéralisation osseuse. L'invention a également trait à des procédés d'utilisation de profils et de signatures génétiques de la minéralisation osseuse, pour le criblage de composés et la recherche. L'invention se rapporte enfin à des réactifs modulant la minéralisation osseuse, destinés tant à un usage thérapeutique qu'à la recherche.

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