Methods and materials for the production of d-lactic acid in...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/14 (2006.01) C12N 1/16 (2006.01) C12N 9/04 (2006.01) C12N 15/81 (2006.01) C12P 7/56 (2006.01) C12P 21/04 (2006.01) C12P 23/00 (2006.01)

Patent

CA 2487296

The present invention relates to biocatalysts that are cells, optimally of the Crabtree-negative phenotype, comprising expression vectors encoding genes heterologous to the cell that enable increased production of organic products. More specifically, the invention relates to genetically modified Kluyveromyces cells, methods for making the Kluyveromyces cells, and their use in production of organic products, particularly D-lactic acid.

Cette invention concerne des biocatalyseurs qui sont des cellules, idéalement du phénotype Crabtree négatif, comprenant des vecteurs d'expression codant des gènes hétérologues à la cellule permettant d'augmenter la production de produits organiques. De manière plus spécifique, cette invention concerne des cellules de Kluyveromyces génétiquement modifiées, des procédés de production de cellules de Kluyveromyces ainsi que leur utilisation dans la production de produits organiques, en particulier d'acide D-lactique.

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