C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/554 (2006.01)
Patent
CA 2398548
The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CEA-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from rectum (Hyseq clone identification numbers 15456780 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CEA-like polypeptides, and antibodies specific for such polypeptides.
Cette invention se rapporte à de nouveaux polynucléotides et à des polypeptides codés par ces polynucléotides, et à des mutants ou variants de ceux-ci qui correspondent à un nouveau polypeptide de type CEA sécrété humain. Ces polynucléotides comprennent des séquences d'acide nucléique isolées à partir d'une bibliothèque d'ADNc provenant de rectums (numéro d'identification de clone Hyseq 15456780 (numéro d'identification de séquence: 1)). D'autres aspects de cette invention concernent des vecteurs contenant des processus permettant de produire de nouveaux polypeptides de type CEA sécrétés humains, et des anticorps spécifiques de ces polypeptides.
Arterburn Matthew C.
Boyle Bryan J.
Drmanac Radoje T.
Kuo Chiaoyun
Liu Chenghua
Hyseq Inc.
Nuvelo Inc.
Smart & Biggar
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