Methods and materials relating to carcinoembryonic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/554 (2006.01)

Patent

CA 2398548

The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CEA-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from rectum (Hyseq clone identification numbers 15456780 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CEA-like polypeptides, and antibodies specific for such polypeptides.

Cette invention se rapporte à de nouveaux polynucléotides et à des polypeptides codés par ces polynucléotides, et à des mutants ou variants de ceux-ci qui correspondent à un nouveau polypeptide de type CEA sécrété humain. Ces polynucléotides comprennent des séquences d'acide nucléique isolées à partir d'une bibliothèque d'ADNc provenant de rectums (numéro d'identification de clone Hyseq 15456780 (numéro d'identification de séquence: 1)). D'autres aspects de cette invention concernent des vecteurs contenant des processus permettant de produire de nouveaux polypeptides de type CEA sécrétés humains, et des anticorps spécifiques de ces polypeptides.

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