Methods and materials relating to cd84-like polypeptides and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 16/00 (2006.01) C12N 9/16 (2006.01) C12N 9/64 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2398546

The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO:1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84- like polypeptides, and antibodies specific for such polypeptides.

Cette invention se rapporte à de nouveaux polynucléotides et à des polypeptides codés par ces polynucléotides, et à des mutants ou variants de ceux-ci qui correspondent à un nouveau polypeptide de type CD84 sécrété humain. Ces polynucléotides comprennent des séquences d'acide nucléique isolées à partir d'une bibliothèque d'ADNc provenant de rates humaines (numéros d'identification de clone Hyseq 2938352 (numéro d'identification de séquence: 1)). D'autres aspects de cette invention concernent des vecteurs contenant des processus permettant de produire de nouveaux polypeptides de type CD84 sécrétés humains, et des anticorps spécifiques de ces polypeptides.

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