Methods and materials relating to novel von...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61P 9/00 (2006.01) A61P 17/04 (2006.01) A61P 17/06 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12M 1/00 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2395770

The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human von Willebrand/Thrombospondin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human fetal brain (Hyseq clone identification number 15258924). Other aspects of the invention include vectors containing processes for producing novel human von Willebrand/Thrombospondin-like polypeptides, and antibodies specific for such polypeptides.

Cette invention se rapporte à de nouveaux polynucléotides et à des polypeptides codés par ces polynucléotides et à des mutants ou variants de ceux-ci, qui correspondent à un nouveau polypeptide humain du type Von Willebrand/thrombospondine. Ces polynucléotides comprennent des séquences d'acide nucléique isolées à partir d'une bibliothèque d'ADNc provenant de cerveaux de foetus humain (numéro d'identification de clone Hyseq 15258924). D'autres aspects de cette invention concernent des vecteurs contenant des processus pour produire de nouveaux polypeptides humains du type Von Willebrand/thrombospondine, et des anticorps spécifiques de ces polypeptides.

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