Methods and materials relating to preadipocyte factor-1-like...

Details Methods and materials relating to preadipocyte factor-1-like... Methods and materials relating to preadipocyte factor-1-like...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C07K 14/00 (2006.01) C07K 14/475 (2006.01) C07K 14/705 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2398215

The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted Pref-1-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from adult human brain (Hyseq clone identification numbers 7958079 (SEQ ID NO:1)). Other aspects of the invention include vectors containing processes for producing novel human secreted Pref-1- like polypeptides, and antibodies specific for such polypeptides.

L'invention concerne de nouveaux polynucléotides, des polypeptides codés par lesdits polynucléotides, et des mutants ou des variants de ceux-ci correspondant à un nouveau polypeptide humain sécrété du type Pref-1. Ces polynucléotides comprennent des séquences d'acides nucléiques isolées d'une bibliothèque d'ADNc du cerveau humain adulte (numéros d'identification de clone Hyseq 7958079 (SEQ ID NO:1)). Selon d'autres aspects, l'invention concerne des vecteurs contenant des processus qui permettent de produire de nouveaux polypeptides humains sécrétés du type Préf-1, et des anticorps spécifiques de ces polypeptides.

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