Methods and means relating to hepatitis b infection

Details Methods and means relating to hepatitis b infection Methods and means relating to hepatitis b infection

G - Physics

01

N

G01N 33/569 (2006.01)

Patent

CA 2549865

The present inventors have discovered that the presence of antibodies reactive with residues 94-117 of the PreS1 component of the hepatitis B surface antigen (HBsAg) in an individual with HBV infection correlates closely with the effectiveness of interferon (IFN) in treating the individual. Methods and means based on this finding are provided herein.

Les inventeurs de la présente invention ont découvert que la présence d'anticorps réagissant avec des résidus 94-117 du composant PreS1 de l'antigène de surface du virus de l'hépatite B (HBsAg) chez un individu infecté par le virus de l'hépatite B est étroitement mise en corrélation avec l'efficacité de l'interféron (IFN) à traiter cet individu. L'invention concerne des procédés et des moyens fondés sur cette découverte.

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