C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/82 (2006.01) A01H 5/00 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01)
Patent
CA 2333432
Means and methods are provided to modulate programmed cell death (PCD) in eukaryotic cells and organisms, particularly plant cells and plants, by introducing of "PCD modulating chimeric genes" influencing the expression and/or apparent activity of endogenous poly-ADP-ribose polymerase (PARP) genes. Programmed cell death may be inhibited or provoked. The invention particularly relates to the use of nuleotide sequences encoding proteins with PARP activity for modulating PCD, for enhancing growth rate of for producing stress tolerant cells and organisms.
L'invention concerne une méthode et un dispositif permettant de moduler la mort cellulaire programmée dans des cellules et des organismes eucaryotes, notamment des cellules végétales et des végétaux. En introduisant des gènes chimères modulateurs de mort cellulaire programmée, lesquels influencent l'expression et/ou l'activité apparente de gènes de la poly(ADP-ribose)polymérase (PARP), il est possible d'inhiber ou de provoquer la mort cellulaire programmée. L'invention concerne notamment l'utilisation de séquences nucléotidiques codant pour des protéines à l'aide de l'activité de la PARP afin de moduler la mort cellulaire programmée, d'augmenter la vitesse de croissance et de produire des cellules et des organismes tolérants au stress.
Babiychuk Elena
de Block Marc
Kushnir Sergei
Aventis Cropscience N.v.
Bayer Bioscience N.v.
Smart & Biggar
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