C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2606296
Aspects of the invention provide methods, nucleic acids and kits for detecting, or for detecting and distinguishing between or among liver cell proliferative disorders or for detecting, or for detecting and distinguishing between or among colorectal cell proliferative disorders. Particular aspects disclose and provide genomic sequences the methylation patterns of which have substantial utility for the improved detection of and differentiation between said class of disorders, thereby enabling the improved diagnosis and treatment of patients.
Des aspects de la présente invention concernent des méthodes, des acides nucléiques et des kits de détection, ou de détection et de différenciation des troubles prolifératifs des cellules hépatiques, ou de détection et de différenciation des troubles prolifératifs des cellules colorectales. Des aspects particuliers de l'invention concernent des séquences génomiques dont les schémas de méthylation sont sensiblement utiles dans la détection et la différenciation améliorées de ces catégories de troubles, ce qui permet d'obtenir un diagnostic et un traitement améliorés pour les patients atteints.
Distler Juergen
Hildmann Thomas
Lesche Ralf
Lofton-Day Cathy
Model Fabian
Epigenomics Ag
Heenan Blaikie Llp
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