Methods and pharmaceutical compositions for enhanced...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61H 31/00 (2006.01) A61K 31/21 (2006.01) A61K 38/11 (2006.01) A61M 16/00 (2006.01)

Patent

CA 2149515

2149515 9411045 PCTABS00032 Methods and pharmaceutical compositions for resuscitating patients suffering from cardiac arrest are disclosed. The methods comprise the performance of cardiopulmonary resuscitation techniques which result in active inducement of venous blood transport into the heart and arterial blood transport from the heart. During the performance of such techniques, the patient is administered with an amount of an arterial constrictor sufficient to increase arterial blood pressure and with an amount of a venodilator sufficient to enhance arterial blood flow to the brain and heart. Pharmaceutical compositions comprise both the arterial constrictor and venodilator present in a single formulation. The methods are found to both enhance patient survival and reduce heart and brain damage.

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